Animal reproductive studies have not been performed with PERCOCET. It's also not acknowledged irrespective of whether PERCOCET can cause fetal damage when administered to some Expecting girl or can have an impact on reproductive capability.
Most of the instances of liver damage are connected to the usage of acetaminophen at doses that exceed 4000 milligrams on a daily basis and infrequently involve more than one acetaminophen-containing solution.
The subsequent are clinically significant drug interactions with oxycodone. This is not an all-inclusive record — other medication not mentioned here may perhaps cause an interaction. Major drug interactions incorporate:
PERCOCET tablets should not be administered to people with recognized hypersensitivity to oxycodone, acetaminophen, or another part of the merchandise.
In minimal doses, acetaminophen could potentially cause elevated liver enzymes. Taking a lot of acetaminophen could cause liver injury or liver failure. The risk of liver harm is better if you already have liver complications, take warfarin, or drink greater than three alcoholic beverages each day.
Store at area temperature away from light-weight and dampness. Various brands of the medication have diverse storage needs. Verify the product bundle for Guidance on how to keep your model, or question your pharmacist. Retain all prescription drugs faraway from little ones and pets.
Key attention need to be offered to the reestablishment of adequate respiratory exchange through provision of a patent airway get more info as well as the institution of assisted or managed air flow. The opioid antagonist naloxone hydrochloride is a selected antidote in opposition to respiratory depression which can end result from overdosage or abnormal sensitivity to opioids, together with oxycodone.
For the reason that duration of action of oxycodone could exceed that from the antagonist, the affected individual needs to be stored underneath continued surveillance, and recurring doses on the antagonist ought to be administered get more info as needed to maintain satisfactory respiration. An opioid antagonist should not be administered inside the absence of clinically significant respiratory or cardiovascular melancholy.
Acetaminophen has been related more info to scenarios of acute liver failure, sometimes causing liver transplant and Demise.
Dosing is determined by your have to have and age, the form of your drug, and click here if the drug is instant-launch or extended-release. The two must be taken only as directed by a healthcare Skilled.
Safety has not been proven in small children; warning or avoidance is instructed in pregnant and breastfeeding Gals as infants is usually born with opioid tolerance and frustrated respirations. On top of that, low concentrations of Percocet have been present in breast milk.
Sufferers who are treated with PERCOCET tablets for various months should be suggested to not abruptly discontinue the medication. Sufferers really should talk more info to with their physician for any gradual discontinuation dose schedule to taper off the medication.
The molecular components for oxycodone hydrochloride is C18H21NO4•HCl and the molecular bodyweight 351.82. It's derived from your opium alkaloid thebaine, and could be represented by the following structural formulation:
Animal studies to evaluate the carcinogenic opportunity of oxycodone and acetaminophen haven't been carried out.